Hey,
10-46 would still be great in my opinion, just it will gradually increase to one semitone tighter on the 27" end, as if you had tuned your low E to F. Well, almost - the 6th string isn't quite 27".
You could always pick up a more balanced set like 10-44 if that exists, which the fan would then stretch out to feel like 10-46.
For the 27" A to match similar gauges you are looking at a 64 or 66
10-46 would still be great in my opinion, just it will gradually increase to one semitone tighter on the 27" end, as if you had tuned your low E to F. Well, almost - the 6th string isn't quite 27".
You could always pick up a more balanced set like 10-44 if that exists, which the fan would then stretch out to feel like 10-46.
For the 27" A to match similar gauges you are looking at a 64 or 66