I have a vypyr too...if I remember correctly, my favorite metal setting is something very close to this (my vypyr is at home and I can't look at the exact LED positions right now):
amp: rec pre: max bass: 10:00 mid: 1:30 high: 12:00
Also, use the pitch shifter with both edit controls at 12:00...you get more bottom end and the sound becomes fuller. Sounds crazy, I know, but just trust me...once you try it, you'll wanna use it on your other patches.
Mesa triple rectifier high mids med bass low treb gain almost all the way up same with presence on mhmmhmmm modern I don't listen to deftones that much sorry