If you have an amp that stays pretty clean it is capable of decent cleans, but if your clean channel breaks up easily it will not be the cleanest sound.
Basically its wicked dynamic, as advertised. Play hard, small amps go into overdrive. It has a really mid range tone so its not going to sparkle but chords do well.
Its somewhat thin compared to the DiMarzio PAF 7 in the neck on my agile but for the same reason its good for metal. pafs get muddy with high gain/low tunings.
Roll of the tone and a comp will the get that bkp bridge to sparkle on anything Probably will no matter how you slice it on a large amp with a good clean.
it's high output pickup so it will brake up clean channel pretty easily on most of the amps, with split coils it reminds me a bit of telecaster bridge pickup type of tone due it's midrange character.
When picking moderately, it works in combination with a Pod HD, especially when rolling off the volume.
It sounds really, really cool if you go for a middle position, combining a fatter neckpickup and the harsher nature of the Painkiller, gets really spanky and smudgy at the same time.