Assuming you were going direct in with your POD X3, I'm pretty sure there shouldn't be any latency because the processing is all happening within the POD and the computer doesn't have to do any work.
I'm guessing you meant PODFarm. In that case, try going to your prefences > audio device settings > ASIO Configuration and change your H/W buffer size to 512. This will slow down your computer a bit, but it should fix your latency problems.