i tend to have a heavier picking hand so i think il go with maybe the 72 or 74s. i recently brought my guitar to drop g and it sounded really muddy so idk if it was due to string gauge or just my amp sucking extremely bad and not handling it.
Try adjusting your pick attack, and maybe even the style of pick. You can get away with some fairly light strings for really low tunings with the right playing style.