50s wraparounds and even 60s lightning bolts are very hard to intonate because they only have the set screws to adjust the overall angle of the bridge. This is why they were replaced with TOMs. Also plenty of lightning bolts are made for wound Gs, so those are actually impossible to intonate. There have since been properly adjustable wraparounds made, but otherwise the ability to intonate is more hypothetical.
They're not that bad. You'll get pretty damn close fairly easily.
As long as you're not going for some oddball, drastically unbalanced sets in some weird tuning, you'll intonate just fine.
This works especially well if you center your intonation point around where you play and not the 12th fret.