I wasn't sure, as I was having a look at various interfaces and saw this for exemple (see attachement): there is a plug labeled MIDI *and* s/pdif.
So I gather this wouldn't be a good one to use the axe fx with ?
That's a non-standard port, so I would guess there's a breakout box that connects to that with separate MIDI and SPDIF ports. Just a guess though
EDIT: OK, I looked it up (checked out the manual for that interface) it does come with a breakout cable for the MIDI and SPDIF connectors